The onset of menstruation is primarily influenced by the method of treatment utilized. For instance, in individuals who have undergone a natural cycle embryo transfer, their period is expected to begin on the usual anticipated date. However, when hormonal medication is administered, the period is likely to commence within two to three days following the cessation of treatment.
In cases where menstruation fails to start within two to three days, it is advisable to seek medical consultation. It is important to note that the initial period following treatment may vary in terms of duration and intensity compared to previous cycles. Therefore, it is crucial to monitor and report any changes to the healthcare provider to ensure proper management.
What Factors Affect the Time og Menstrual Bleeding?
The timing of the menstrual period following in vitro fertilization (IVF) can vary depending on several factors, such as the type of IVF cycle, the use of medications, and individual differences among patients.
In a natural cycle IVF, where no hormonal medications are given to stimulate ovulation, the menstrual period should start around the usually expected date. In contrast, in a stimulated IVF cycle, where medications are administered to stimulate the ovaries to produce multiple eggs, the period typically begins two to three days after the medication is stopped. However, the exact timing can vary, and it is important to follow the instructions provided by the healthcare provider.
If menstruation fails to start within two to three days after stopping the medication, patients should seek medical advice. It is also worth noting that the first period after IVF treatment may be different in duration and intensity than usual. Patients should monitor any changes and report them to their healthcare provider.
When Should the Egg Collection Cycle be Repeated If it Fails?
Not all attempts at IVF are successful on the first try, and it may take several cycles before achieving success. If the outcome of the first cycle is not ideal, patients can try again after discussing it with their IVF doctor.
Following the egg collection process, the patient’s ovaries require a period of rest, and menstruation is expected to begin about 1-2 weeks after the collection. The earliest time to attempt another cycle will be during the next menstrual cycle, as this allows the ovaries to rest and recover fully.
Success rates of embryo transfer depend on several factors, including the thickness of the endometrial lining and embryo grading. If the hCG test after the first attempt is negative, menstruation is expected to begin within a week. However, patients can discuss with their IVF doctor to determine the best timeline for their specific situation. If they require more time before attempting another cycle, they can discuss options with their doctor.
What are the Post-Failure Factors?
The ovarian factor involves modifying and customizing new attempts based on hormone levels and previous ovarian response, while progesterone levels can indicate optimal endometrial receptivity. Repeated implantation failure can be caused by various factors related to the endometrial factor such as abnormalities in the intrauterine cavity, poorly proliferated endometrium, endometritis, immunological factors, and blood coagulation abnormalities.
In a new attempt, certain parameters related to semen quality that can influence fertilization rate should be considered, even though ICSI can be carried out with a low number of spermatozoa. Embryo quality is determined by the degree of expansion and quality of cells of embryos that reach the blastocyst stage, and good-quality embryos have a higher chance of leading to pregnancy. The IVF laboratory must maintain optimal conditions for embryo development by ensuring quality control in factors such as air quality, pH, incubators, lighting, and media used for culturing embryos. Finally, the experience of embryologists is also important in the success of IVF treatments.
Romanski, P. A., Bortoletto, P., Rosenwaks, Z., & Schattman, G. L. (2020). Delay in IVF treatment up to 180 days does not affect pregnancy outcomes in women with diminished ovarian reserve. Human Reproduction, 35(7), 1630-1636.