"Dr. Aygün has performed more than 13.000 egg retrieval procedures in the last 7 years: an almost unattainable feat.''
“Patient happiness represents the real success rate."

Dr. Melih Aygün has been working as an infertility specialist, and obstetrician & gynaecologist for more than 24 years. After obtaining medical degree in Turkey and doing his residency in Obstetrics and Gynaecology, he continued his studies in the Department of Gynecological Endocrinology and Reproductive Medicine of the University of Vienna, where he had the opportunity to combine different disciplines together and gain significant international experience. He holds a board certification for assisted reproductive technologies and treatments, and his professional experience comprises working in reputable IVF centers in Turkey. He is renowned for promoting a gentler approach to fertility, offering couples the best chance of success while helping reduce the emotional and physical burden associated with infertility treatments. His methodology includes both low-tech and more progressive technology processes.

He professes an honest, ethical approach and ensures his patients have realistic expectations from the onset of the treatment.

Today, he combines his expertise with that of his brother, Mehmet Aygün, a perinatology specialist. Both of them work at the Erasmus Fertility and Women’s Reproductive Health Center, which they established in 2005. Using state-of-the-art technologies, He guides his patients through the entire process, from preconception until delivery.   

Dr. Melih Aygün is married and has three children.                                                        

He speaks German and English.

Message from Dr. Aygün

“I feel incredibly grateful to be a part of so many couples’ journey into begetting their own children.”


FERTILITY Evaluation

The first step in any fertility journey is our fertility assessment.
Ultrasonographic examination, hormones, semen analysis, hysterosalpingography, genetic analysis, serology


In vitro fertilization/intracytoplasmic sperm injection
Involves hormone injections to stimulate ovaries, egg retrieval, fertilization and cell division, embryo transfer and embryo freezing


Preimplantation Genetic Diagnosis / Screening
Genetic testing on blastocyst stage embryos including a trophectoderm biopsy, in conjunction with an IVF/ICSI cycle, prior to implantation.


EGG Freezing

“owning your future”
Freezing eggs for fertility preservation with utiling assisted reproductive technologies


Check reproductive congenital or acquired abnormalities leading infertility such as polyps, cyctes, endometriomas, fibroids, adhesions...etc.

MALE Infertility

Evaluation of male infertility
Collaborating with the most experienced urologists specialized for male infertility:


IUI (Intrauterine Insemination)
Ovulation induction
Medical treatments



Intend to re-awake egg maturation and development within the ovary in order to achieve pregnancy in women with Premature Ovarian Insufficiency (POI).

  • Modified Ovarian injury
  • Foods&Supplements


Genetic testing of embryos can increase chances for having a successful pregnancy without a specific genetic condition or chromosomal abnormality.

  • PGT-A for aneuploidy
  • PGT-M for single gene disorders
  • NGS (Next-Generation Sequencing)


Blastocyst stage embryos (day 5) have better implantation rates:
better embryo–endometrium synchrony
Identifying embryos with development potential.


Frozen Embryo transfer has high pregnancy rates with less potential complications in comparison to fresh embryo transfer.


Continuous monitoring of embryo development from day 1 to day 5 helps to select the best embryo.


Observation of spermatozoa by High-magnification microscope:
Selection of the better quality sperms improve the pregnancy rates and lower the miscarriage rates.


It is the revolutionary male infertility treatment. On the experienced hands, it yields the highest sperm retrieval rates in non-obstructive azospermia (NOA).

SPERM Chip (Micro Chip)

This new method probably allows natural sperm selection and the better DNA quality sperm for IVF/ICSI.





“Everything you can imagine is real.”

Pablo Picasso

Top IVF Doctor in Turkey, Because Most Trustable One

He is the best doctor, not only in Istanbul, but all over the world. From my personal experience and not having children for seventeen years, I visited many doctors around the world, but I did not find a better one than Dr. Melih Aygűn… He performed many successful IVF operations for years Therefore, those who received treatment on his hand advised us to come to him, and thank God, everything is perfect, thanks to God and His grace
We came for IVF treatment from USA, it was very nice that Dr. Melih speaks English. All treatment time he was involved in care by himself from initial assessment through the end, not as other doctors working through nurses. Dr. Melih cares for best outcome with all his heart. What impresses us the most is that he is always available any time for any questions. After we left Turkey and came to USA he is still involved in care. Even though, we have a time difference and sometimes texting late at night or early in the morning, he always answers fast. He is very patient and answers all crazy questions I have. Also we enjoy hospital where egg retrieval and transfer was performed.Hospital is new with newest equipment. Rooms were clean, and nicely designed. Even though we didn’t stay long , they served nice food. We are very happy we chose Dr. Melih.
We are so lucky to come across Dr. Aygün! Extremely knowledgeable, very attentive and understanding. As soon as we started thinking about having a second child and consulted with him, he has been very much supportive and instructive. Every time we had any kind of question, he would get back to us right away. I can go on and on.
He guided us through every step of this IVF process and honestly, this is what every couple wants from a doctor, especially during this time when you’re most overwhelmed, vulnerable and most emotional. Every woman who is going through the IVF process or thinking about it, knows exactly what I’m talking about. I must specifically emphasize this; I didn’t get this kind of treatment first time around in the United States. Patients coming from the US know that doctors aren’t always very attentive; in fact, you’re lucky if you get to talk to a doctor ever enough unless you personally know them or you can afford your personal doctor! I have always felt great anytime I was around Dr. Aygün and his team.
Side note; Dr Aygün has one of the top embryologists in the world on his team. Every stage of IVF process from the start of the injections to the egg retrieval to the embryo transfer in every single step of the way, his guidance and attentiveness was outstanding. We can not thank Dr. Melih Aygün enough for everything he has done for us! Currently I am waiting for my pregnancy result 🙂


“Feeling comfortable with your treatment and hopeful about the future is our mission”

Not all patients will need IVF services.
State-of-the-art facilities
Creating bespoke treatment plans and responding to individual patient or couple needs.
Providing an environment where you can feel confident asking questions, expressing concerns, and openly discussing procedures.
Avoiding a “production line” feel in any infertility center.
Maximizing your chances of having a healthy baby while minimizing the stress.
Knowing your care will be directed by Dr. Melih Aygun from beginning to end.


“Real success rate is happy patients”.

Reasons of our success:
All of the examinations are performed only by one specialist.
Committed to treating in compassionate manner
Involving state-of- art technology and procedures
Long experience and wide knowledge


“Over 13.000 egg retrieval procedures during IVF treatments in the last 7 years;

an almost unattainable experience.”

Board certificated specialist for IVF treatments and 23. years experience of ART.
National work experience in most successful ivf centers
Internatianal work and fellowship experience speaking English and German
A part of more than 5000 babies have been born through fertility treatments
Over 13.000 egg retriveal procedures during IVF treatments in last 7 years
Developed high expertise in the successful egg retrieval procedure with the lowest complication rates in IVF

Latest Posts

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What is the use of Progynova in IVF?

Progynova is a medication that contains estradiol valerate as its active component. Essentially, Progynova refers to tablets of estradiol, which is considered the primary female hormone, and is taken orally to be absorbed by the body. (1) What is Estradiol? Estradiol is a hormone that is naturally produced by the follicle, which is the structure that develops in the ovary…

What happens during reciprocal IVF?

As the field of reproductive medicine and fertility options continue to advance, having a child is becoming increasingly attainable. There are now more options than ever before for those looking to start a family. One option that is gaining popularity among same-sex female couples is reciprocal in vitro fertilization (IVF), which is also known as co-IVF, co-maternity, or reception of…

“Miracles comes through in this city throughout the history’’

O. Pamuk, Istanbul
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2nd Opinion