The level of anti-mullerian hormone (AMH) in the blood is measured by an AMH test. AMH is produced by both malesand females . But the test is frequently used by medical professionals to give an overview of women’s reproductive health.
You can find out through an AMH test how many eggs you still have and whether your ovaries are aging too quickly. As you prepare for in vitro fertilization (IVF), it can also show how well you will respond to injectable and fertility medicines that help your ovaries to produce many eggs. (1)
What is the anti-mullerian hormone (AMH)?
Granulosa cells in ovarian follicles secrete the hormone AMH. The procedure is initially carried out in primary follicles that develop from the primordial follicle stage. The follicles are microscopic at this stage and are invisible to ultrasonography.
In the preantral and tiny antral stages of development, AMH production is highest (less than 4 mm in diameter). As the follicles develop, production slows and eventually stops. Nearly little AMH is produced in follicles larger than 8 mm. Since levels are essentially consistent, as a result, the AMH test can be performed on any day of a woman’s cycle. (2)
What is the connection between AMH levels and pregnancy chances in IVF treatment?
Women with higher AMH readings typically respond to ovarian stimulation more favorably and produce more eggs for IVF in Turkey. In general, IVF success rates are higher when there are more eggs available.
AMH levels probably don’t provide much information regarding egg quality, but the more eggs collected the better. Consequently, there is a higher likelihood that at least one healthy embryo will return to the uterus. (3)
What is a normal AMH level?
It can be interpreted in conjunction with the levels of the anti-mullerian hormone and the chance of conception. The levels considered “normal” have not yet been clarified and are not agreed upon by all professionals due to the test not being used frequently for a long time. (4)
However, depending on your age, different AMH levels may be considered to be normal. Women’s AMH levels begin to increase around puberty and reach their peak around age 25. Following then, levels of AMH naturally decrease.
The amount of AMH is measured by providers in nanograms per milliliter (ng/mL). Although professionals debate on how to define normal AMH levels, the following ranges are generally accepted as normal:
- Average: Between 1.0 ng/mL to 3.0 ng/mL.
- Low: Under 1.0 ng/mL.
- Severely Low: 0.4 ng/mL.
It’s crucial to keep in mind that since different labs utilize different technology, your results may somewhat vary from lab to lab. (5)
What is a good AMH level for your age?
In your 30s, 40s, and 50s, you should expect to see a decrease in your ovarian reserve because AMH levels normally diminish with aging.
Consider these lower-end estimations for each relevant age in terms of actual numbers:
- 25 years old: 3.0 ng/mL.
- 30 years old: 2.5 ng/mL.
- 35 years old: 1.5 ng/mL.
- 40 years old: 1 ng/mL.
- 45 years old: 0.5 ng/mL.
AMH levels that are higher are not always advantageous. Some people with Polycystic Ovary Syndrome (PCOS) may have very high levels of AMH which will considerably increase the risk of ovarian hyperstimulation syndrome (OHSS). (6)
Does vitamin D increase AMH?
Vitamin D is crucial for sustaining both bone health and general wellness. Although the connection between vitamin D and AMH is not totally obvious, some data points to the possibility that vitamin D may also be important for female reproductive health.
AMH levels and vitamin D levels have been observed to positively correlate in several studies, indicating that vitamin D may elevate AMH. Other research, however, has not found a strong connection between vitamin D levels and AMH levels. Further research is required to conclusively link vitamin D and AMH levels because the mechanism by which it may do so is not fully understood.
It’s crucial to remember that, even while vitamin D may be vital for female reproductive health, fertility treatments shouldn’t solely depend on it. Age, ovarian reserve, and general health are additional elements that have a big impact on fertility.
Therefore, additional research is required to establish a clear connection between vitamin D intake and AMH levels, even if there is some evidence to support this. The appropriate course of action for each individual case should be discussed with the healthcare professional by women who are worried about their fertility.
La Marca, A., Broekmans, F. J., Volpe, A., Fauser, B. C., & Macklon, N. S. (2009). Anti-Müllerian hormone (AMH): what do we still need to know?. Human reproduction, 24(9), 2264-2275.